When is the most impactful time for teammates to combine their powerful 'ultimate abilities' in a synergistic sequence?

The most impactful time for teammates to combine their ultimate abilities in a synergistic sequence is typically at the initiation of a critical team engagement, specifically when advantageous conditions align to maximize their combined effect. An 'ultimate ability' is a character's most powerful skill, characterized by a long cooldown and significant, often area-wide, impact. A 'synergistic sequence' involves activating multiple ultimate abilities in a specific order where one ability directly enhances or enables the effectiveness of the subsequent ones, creating a greater overall impact than if used individually. The optimal moment for this combination occurs when enemy combatants are grouped closely together, rendering them vulnerable to area-of-effect abilities, and when their key defensive or crowd-control abilities are on cooldown, preventing them from disrupting the sequence. Furthermore, this timing is most potent during crucial objective contests, such as securing a capture point, pushing a payload, or engaging a neutral boss, where the immediate, overwhelming power can decisively win the objective. For instance, an ultimate that gathers or stuns multiple enemies, often called a 'setup ultimate,' should be immediately followed by a high-damage or debilitating crowd-control ultimate, known as a 'payload ultimate.' This ensures the payload ability impacts the maximum number of immobilized or vulnerable targets, converting the combined ultimate use into an immediate and often fight-winning advantage by eliminating key threats or securing a critical position.