The primary mechanism by which amphetamine increases dopamine levels in the synapse is through its action as a substrate and releasing agent at the dopamine transporter (DAT). The synapse is the space between two neurons where neurotransmitters are released. Dopamine is a neurotransmitter involved in reward, motivation, and motor control. The dopamine transporter (DAT) is a protein located on the presynaptic neuron that normally fu....
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