Which neurotransmitter system, beyond dopamine and norepinephrine, is significantly affected by cocaine, contributing to its addictive properties?
Beyond dopamine and norepinephrine, the serotonin neurotransmitter system is significantly affected by cocaine, contributing to its addictive properties. Cocaine acts as a reuptake inhibitor for serotonin by blocking the serotonin transporter (SERT). The serotonin transporter is responsible for removing serotonin from the synapse back into the presynaptic neuron. By blocking....
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