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Explain the mechanism by which immunosuppression increases an individual's susceptibility to developing oral cancer.



The human immune system constantly performs a vital process called immune surveillance, which involves continuously monitoring the body for abnormal cells, including those that are pre-cancerous or have undergone malignant transformation. Specialized immune cells, primarily cytotoxic T-lymphocytes, also known as killer T-cells, and natural killer (NK) cells, are crucial in recognizing and eliminating these potentially harmful cells before they can develop into overt tumors. Immunosuppression refers to the weakening or deliberate suppression of this immune system, often induced by medications given to organ transplant recipients to prevent rejection, or for individuals with autoimmune diseases, or as a consequence of certain medical conditions like HIV/AIDS. When the immune system is suppressed, its ability to carry out this essential immune surveillance is severely compromised, directly increasin....

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